AIMAC 2015


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  • The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight-loss in addition to a reduced-calorie diet and physical exercise.

    Using two separate drugs to shed weight can be very effective you will find combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the people that go through it one should err assisting caution and let the FDA do its job and demand some research be done in order that the public is aware of the side effects and risks of the medications before we drive them. Keep in mind that drug companies come in business to generate money and that they would say anything to keep people on their medications.

    Researchers discovered that participants using this drug for the year, lost weight within four weeks and have kept the extra weight off during the entire 56 weeks of the study. Contrave is really a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which are made up of many active ingredient, that might make them more efficient and safer.

    Combo-pilling is the newest fad or even better the newest into the future under scrutiny and for that reason it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is now popular will be the fact that since right now there aren't any long term prescription diet pills that have been licensed by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be authorized by the FDA.

    Seizures really are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug also can raise blood pressure level and heartrate, and mustn't be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise blood pressure and pulse rate and must 't be used in patients with uncontrolled high blood pressure, as well as by a person with heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients using a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients towards the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking.

    New UCLA study on smokers with mental, drug, and alcohol problems